OUR LOCATION:
The center is located in the Faculty of Medicine- Mansoura University.
E-MAIL: عنوان البريد الإلكتروني هذا محمي من روبوتات السبام. يجب عليك تفعيل الجافاسكربت لرؤيته.
FAX: 050-2227371
MOBILE: 01150646219
OUR LOCATION:
The center is located in the Faculty of Medicine- Mansoura University.
E-MAIL: عنوان البريد الإلكتروني هذا محمي من روبوتات السبام. يجب عليك تفعيل الجافاسكربت لرؤيته.
FAX: 050-2227371
MOBILE: 01150646219
1- Development of Experimental Scientific Research in Faculty of Medicine, Mansoura University.
2- Raise awareness of the importance of empirical research among students, alumni, faculty members and their assistants.
3- Opening up the work of scientific research cooperation between the University of Mansoura, universities and scientific research centers, homeland.
4- Scientific cooperation with the international scientific centers.
5- The events of integration and compatibility between the basic research disciplines and interdisciplinary clinical Faculty of Medicine, Mansoura University.
6- Activating the empirical research university and marketing adopted after the research projects with a national moving implementation of the protocols of interest to the university research.
7- The implementation of workshops for the departments of clinical use of experimental animals
Implementation of local training courses and international empirical research for young researchers.
MERC annual Report 2021
(1) Thesis & free researches “total 27”
• PHD (7)
Mansoura Faculty of Medicine (5).
Beni Sweef Faculty of Medicine (1).
Mansoura Faculty of Veterinary Medicine (1).
• MsC (10)
Mansoura faculty of Medicine (5).
Mansoura faculty of Pharmacy (1).
Mansoura faculty of Dentistry (3).
Mansoura Faculty of Veterinary Medicine (1).
• Free researches (10)
Mansoura faculty of Medicine (7).
Mansoura faculty of Dentistry (2).
Mansoura Faculty of Veterinary Medicine (1).
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(2)Training courses “total 2”.
• Mansoura-Manchester Programme training (2)
• Mansoura faculty of Veterinary Medicine summer training (1)
(3)Projects funded by scientific institutes- still running“total 5”.
• Upgrading and Accreditation of the Medical Experimental Research Center of Mansoura University (MERC).
Funded by: STDF.
PI: Dr\ BasemAwad.
• Novel therapeutic strategies for tauopathies.
Funded by: STDF.
PI: Dr\ Sara ElFarash.
• Novel Nano-Structured Enabled Drug Delivery System for the Treatment of Tauopathy in animal model.
Funded by: Academy of scientific research and technology
PI: Dr\ RandaElgamal
• Autophagy and a Possible New Neuroprotective Therapies ina Mouse Model of Parkinson’s Disease.
Funded by: Mansoura University.
PI: Dr\ Amira El Adl.
• A new method for characterizing adult mesenchymal stem cells used for medical injection, using pleuripotency gens profile.
Funded by: Mansoura University.
PI: Dr\ Dalia Mustafa.
• Nrf2 as therpeautic target for Alzehimers disease associated Tauopathy"
Funded by: Mansoura University.
PI: Dr\ Sara El Farash.
(4)Grants – still running – 5 groups “total 1”
1- Long – term immunity in SARS-Cov2 recovered patients with history of HCV
PI: Mohammed Magdy Mowafy
2- Modulating autophagy by liragutide in ulcerative colitis, a promising therapeutic approach
PI: Ahmed Attif Saadon
3- Studying the role of miRNA – 27 A AND miRNA 21 in development and progression of breast cancer: an experimental study
PI: Ahmed Mahmoud Eldosouki
4- IL- 6 in exhaustive exercises and its correlation to bacterial infections: a comparative animal study
PI: Amr Ali Abdo
5- Role of neuro- inflamition in pathogenesis of alzehimers disease associated taupathy : implication for a future gene of immune – therapies
PI: Ahmed Sabry Ibrahim
(5) Scientific publishing
Summer grants in Medical Experimental Research Center (MERC)
((المنح الصيفية بمركز البحوث الطبية التجريبية ))
From 2010 Till 2018
• Students: Ahmed El-kholi – Ahmed Ghoniem (Medicine)
• Research: Effect of Bone Marrow Mesenchymal Stem Cells on Sepsis Induced Acute Kidney Injury in Sprague Dawley Rats
• Conference: European Society of Nephrology in paris, france 24:27 May 2012
• Students: Sherif Shawer – Mahmoud Nosseir (Medicine)
• Research: Experimental Renal Ischemic/Reperfusion Injury in Rats; Does Gender Have Any Effect?
• Conference: International Conference on Research and medical students in Amsterdam, Netherlands 4:8 June 2012
• Student: Amr El-laithy – Basem Helmy (Medicine)
• Research: Does colchicine possess a neuroptective effect in parkinson’s disease
• Conference: International Student Conference of Medical Sciences (ISCOMS), Netherlands 4:8 june 2012
• Students: Ahmed Amer – Omar Hassan (Medicine)
• Research: Acute Kidney Injury Complicating Hepatic Ischemia Reperfusion Injury in Rats: Study of Continuous Versus Intermittent Hepatic Clamping
• Conference: 23 European Students' Conference held in Berlin, Germany, 17: September 20, 2012
• Students: Hazem Kassem – Mohamed Osama (Medicine)
• Research: Hepatic Injury Induced by Renal Ischemia-Reperfusion (I/R) Injury: Possible Role of Nitric Oxide
• Conference: CRRT that endorsed by ISN (International Society of Nephrology) and AKIN (Acute Kidney Injury Network) San Diego, California 12:15 February 2013
• Students: Amany Abo Zahra – Aya Abd Elkhabir (Medicine)
• Research: Pancreatic injury induced by I/R injury: possible role of oxidative stress
• Conference: American Society of Sugar Dubai, United Arab Emirates 4:6 December 2012.
• Students: Sara Abo Elfath – Sally farag (Medicine)
• Research: TLR-4: “Trojan Horse” in AKI induced encephalopathy
• Conference: European Society of Nephrology in paris, france 24:27 May 2012
• Student : Mahmoud El-kotb Abd El-Meged Elhussiny (Medicine)
• Research: Neurons Loss in Parkinson’s Disease: How Much sex Hormones Decline Contribute To?
• Conference: American Academy of Neurology 66th Annual Meeting pennsylvania , philadelphia 26 April to 3 May2014.
• Student: Eman Youssef Abo Elyazeed (Dentistry)
• Research: The Effect of TEC on Neurospheres
• Conference: Eurotox Conference 2014” in Edinburgh, Scotland 7-10 September 2014
• Students: Maria Aziz Youssef (Medicine)
• Research: Malathion affects proliferation neural progenitor of rat
• Conference: 18th congress of the European society for toxicology in vitro Netherlands 10:13 june 2014
• Student: Mohamed Elhosseny (Medicine)
• Research: Expoximicin Affects The Proliferating Neural Progenitor Cells of Rat
• Conference: Cancer Stem Cell Conference 2014 in Cleveland, Ohio United States of America 17-20 August 2014
• Student: Mohamed Adel Mokhtar (Medicine)
• Research: Effect of Piericidin Toxin on Neurospheres, in vitro Study
• Conference: 25th European students conference (ESC) in Berlin, Germany 17:20 September 2014
• Student : Islam Emad Elkholi (Medicine)
• Research :Nanomedicine and Challenges of Cancer Theragnosis
• Essay : Nanomedicine and Challenges
• Conferance: (Nano4life) As aprize for being selected as one of the 2 only winners of the international
• essay competition. British Society for Nanomedicine London, United Kingdom 15 May 2013.
• Student : Islam Emad El-kholi (Medicine)
• Name of Research : Capsaicin-loaded smart nanoparticles induce apoptosis in HepG2 hepatocarcinoma cells.
• Conferance : 12th international congress on targeted Anticancer Therapies (TAT 2014) washington, USA, 5 -7 March 2014
• Student : Eslam Hamza Mohamed Zaky (Medicine)
• Research : Diatery supplementation as a neuro protective therapy in treatment of Parkinson’s disease in rotenone models in mice.
• Conferance: Annual meeting of the International Society for Science neurobehavioral Las Vegas, Nevada, United States of America 10:15 june 2014
• Student : Moataz El-laithy – Lina Mohamed Ali – Dina Shouky (Medicine)
• Research: The Role Of TLR-4 In APAP-Induced Organ Damage
• Conference: American Society of in toxins Arizona, USA 21:27 march 2014
• Student : Salma Ismail (Medicine)
• Research: The Effect of Trichloroethylene on the Neurosphere
• Conference: 25th European students conference (ESC) in Berlin, Germany 17:20 September 2014
• Student : Bahaa El-Den Awad Ahmed (Medicine)
• Research : Epoxomicin affects proliferating neural progenitor cells of rat
• Conference: “Cancer Stem Cell Conference 2014 in Cleveland, Ohio United States of America 17-20 August 2014”
• Student : Mohamed Yasser Elsherbiny (Medicine)
• Research: Effect of papaverine on Developmental Neurotoxicity:Neurosphere as in vitro model
• Conference: : 25th European students conference (ESC) in Berlin, Germany 17:20 September 2014
• Student : Khaled Nasr Eldin Bakr (Medicine)
• Research: Epoxoimicin Affects The Proliferating Neural Progenitor Cells of Rat
• Conference: : 25th European students conference (ESC) in Berlin, Germany 17:20 September 2014
• Student : Hossam Mohamed Farid (Medicine)
• Research: Papaverine Overdosage Can Predispose to Neurodevelopmental Disorders
• Conference: : Eurotox Conference 2014” in Edinburgh, Scotland 7-10 September 2014
• Student : Mohamed M. El-Hawary (Medicine)
• Research: Effect of Environmental Toxin (Piericidin) on 3D Neurosphere Culture; In Vitro Study
• Conference: Society for Neuroscience (SfN) Annual Conference 2014 in Washington” 15-19 November 2014
• Student : Hossam Hamza Elbelasi (Medicine) & Hossam Mohamed Eid (Science)
• Research: Curcumin and its Derivatives as novel pharmacological treatment for human breast cancer cell line, in vitro study"
• Conference: NCRI Cancer Conference 2014 in Liverpool, England 2:5 November 2014.
• Student : Ahmed Omar Nazal(Medicine) & Mahmoud Abd Elsamie Warda (Medicine)Sara Mohamed Anter(Medicine)& Mona Faried Hosh(Medicine)
• Research: Manipulation Of Gut Brain Axis In Toxic Model of AD -2015.
• Student: Esraa Elsayed Mostafa(Medicine) & Hazem Kassem Khaled(Medicine) Mahmoud Tawfeek(Medicine).
• Research: -protective effects of oral colchicines in Alzheimer’s – induced Dementia in STZ Rat model-2015.
• Student: Ahmed Abd El Warth(Dentistry Mansoura)& Yosra Mohamed Faried (Dentistry Mansoura) Mohamed Gamal Elbeltagy
(Dentistry Mansoura)& Hager Taher Elhawary (Delta)& Malak Shrief Mohamed(Delta)& Manar Zaher(Delta).
• Research: the impact of Dentin chips and Bone on Bone Marrow Mesenchymal stem cells using low level laser”. (between Mansoura Univeristy and Delta Univeristy) -2015.
• Student: Ahmed Atef Elbayar(Medicine) & Amr Hany Elmatwly(Medicine) Mohamed Abd Elrahman(Medicine) & Ahmed ElShair(Medicine) Ahmed Abd ElMaosoud(Medicine) & Ali Alshenawy(Medicine) & Noran Saad eldeen (Medicine) Mohamed Hossam Eldeen (Medicine).
• Research: Spinal Cord injury research team - 2015.
• Student: Mohamed Gamal ElBeltagy(Dentistry)
• Research: " Dental plup stem cell isolation, tissue culture, characterization and cryopreservation from human tooth"
• Conference: "7th Annual conference on Stem Cell & Regenerative Medicine" held at Manchester United Kingdom at 4 -5 August 2016.
• Student : Khaled Magdy Sadek (Medicine)
• Research: 1- Beta Lactams Antibiotic ceftriaxone Modulates Seizures, Oxidative Stress and Connexin 43 (cx43) Expression in Hippocampus of Pentylentetrazole Kindled Rats.(Published in Journal of Epilepsy Research)
2- Role of Oxidative Stress, Neuroprotective Heat Shock Protein 70 and Connexin 43 in Pentylenetetrazole-induced Seizures in Rats: Possible Protective Effect of Ferulic Acid"
• Conference: 12th European Congress On Epileptology in Prague 11-15 September 2016.
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2010:2016
(26 طب – 3 اسنان – 1 علوم )
2017
تم اختيار 15 طالب من طب ولم تكتمل .
(2018)
1- siRNA Blocking of Mammalian Target of Rapamycin (mTOR) Attenuates Pathology in Annonacin-Induced Tauopathy in Mice
(Khaled Magdy sadek 6th year student)
2- FOXRED1 silencing in mice: a possible animal model for Leigh syndrome FOXRED1 silencing in mice: a possible animal model for Leigh syndrome
(Abdelrahman Moustafa 5th year student)
Basic Science Research – Student opportunity-
“CENTER OF EXCELLENCE GRANT” (2020)
Mansoura Manchester program for medical Education (MMPME) administration in collaboration with the Medical Experimental Research Center (MERC) are providing the opportunity to support 5 research grants dedicated to medical students in Faculty of Medicine- Mansoura University. Grants are funded and supported exclusively by MMPME.
The program aims to encourage Mansoura faculty of medicine students to be engaged in a well-adjusted research environment that provides you with the basics of medical research, teamwork, scientific writing, and publishing.
Regarding the Scope of research, applications from all areas of medical science will be considered. The submitted proposals should be in basic research pertaining to the broad area of health care and under the supervision of staff member at Mansoura faculty of medicine. All the remaining terms and conditions are mentioned attached file on your MOODLE page (Eligibility criteria, Dates, Fund, Proposal structure, selection process, and project evaluation).
تم قبول الطلبة المتقدمين للمنحة وتقسيمهم على 5 مجموعات
Beside the main objective of MERC which is “conducting a high quality research” we are pleased to offer various training and continuous education activities as follows:
1. Egyptian Network for Neurodegenerative Disorders (ENND):
MERC is the coordinating nucleus for ENND, through this we are organizing a yearly translational summer school which connect 30 Egyptian students with international speakers from all-over the world. Students are funded totally for free registration and accommodation.
More important ENND supports the travel of three Egyptian postgraduate students -yearly- to Munich for training on various basic and clinical techniques in Technical University of Munich and German Center for Neuro degenerative disorders.
2. Different hands on training workshops e.g. workshop on stem cells isolation, microsurgical techniques, animal handling etc.
3. IBRO (International Brain Research Organization). activities: currently, MERC is a center of excellence for IBRO-MENA chapter. Through this, MERC is planned to receive scholars- who are funded from IBRO to study certain techniques e.g. cell culture, stereotaxis aided brain surgeries – from different countries of Middle East.
MERC organizes yearly IBRO school who receives students from Africa and Middle East and offer them access to pioneers in the field from all over the world.
4. MERC supports training of undergraduate students through offering summer grants to join research teams in MERC. Through this program, different students had the opportunity to publish their works in international journals. More recently, two students from MERC were invited to present their work as a webinar for Middle East Molecular Biology Society (MEMBS) educational resources.
5. TReND in Africa Focal Point: MERC is the focal point for TReND in Africa inside Egypt. Main aim of TReND is to support the short stays of volunteers from European institutions to transfer knowledge and offer training for African students. MERC is waiting the first visit by Dr. Natalie Doig (Oxford University) who will be the first expert visiting MERC through this European Union funded program.
6. Tranlsational Neuroscience Summer School II (TNSS), Hurghada september 24-28th, 2017. the school supported 30 students from allover Egypt plus a variety of international and national faculty. 3 students were awarded short term scholarships for travel to Munich Germany.
7. Neuroethics symposium (MERC, IBRO, AUC) November, 28,29th 2017
Based on ongoing research in MERC, publication process is a continuous process.
From 2011 till 2020 MERC succeeded to produce the following HIGH QUALITY RESEARCH:
German Center for Neurodegenrative Diseases (DZNE, Munich):
https://www.dzne.de/en/sites/munich.html
The collaboration with DZNE, Munich is coordinated through Translational Neurodegeneration Department. For five years MERC and DZNE has been involved in DAAD funded projects to characterize genetic and epidemiological factors controlling Parkinson’s disease.
Department of Pharmacology and Cancer Biology, Duke University Medical Center:
http://pcb.duke.edu/
For about four years, MERC in collaboration with Pharmacology and Cancer Biology, Duke University, are trying to develop new biomarkers for diagnosis of brain damage. The collaboration has been generously funded by IBRO, ISN, Mansoura University Competitive Grants Program and Academy of Scientific Research and Technology (ASRT).
Luxembourg Center for Systems Bioscience (LCSB):
http://wwwen.uni.lu/lcsb
LCSB and MERC are currently involved in establishment of a new bioinformatic center and integrated biobank for future application in research in the biomedical field.
Genetic Epidemiology of Parkinson’s Disease (GEoPD):
http://geopd.can.ubc.ca/
MERC is currently the newest member of GeoPD and is considered the first member in the Middle East. The main goal of this collaboration is to identify novel environmental and genetic risk factors for PD in Africa.
Department of Chemical Engineering, Northeastern University, USA:
http://www.che.neu.edu/che/about-chemical-engineering
This collaboration aims to explore the possibility of applying nanotechnology in regenerative Medicine.
Global Brain Health Institute (GBHI) USA
http://www.gbhi.org/
Aiming at fighting dementia worldwide
Hokkaido University, Japan
http://www2.hokkyodai.ac.jp/english/
Aiming at studying the immunogenetic profiles for Parkinson’s patients derived fibroblasts
IBRO-MENA:
MERC was chosen as IBRO MENA center of excellence in Egypt. For training and education of students from Middle East
- Lubek – University Germany